Oral semaglutide + tirzepatide
both actives, one daily dose.
A compounded oral combination pairs semaglutide and tirzepatide in a single daily dose taken by mouth. Through Surfbound Health it starts at $365/mo, all-inclusive, after licensed provider review. No FDA-approved combination exists.
- Combination — from $365/mo
- Single daily oral dose
- No weekly injections
- No membership fee
Prescription required. Not everyone qualifies. No clinical trial has studied semaglutide and tirzepatide taken together. Compounded medications are not FDA-approved.
Oral combination pricing
Compounded semaglutide + tirzepatide, taken daily.
1-month supply
$3653-month supply
$10056-month supply
$1895- Medication included if prescribed
- Provider review included
- No membership fee
- Discreet shipping included
Treatment determined by licensed providers. Not all patients qualify.
What it is
One daily dose, two GLP-1 actives
The compounded oral semaglutide + tirzepatide combination places both semaglutide and tirzepatide in a single daily oral format. It is designed for people who want to avoid injections and prefer one combined dose to managing two separate medications.
Two actives in one dose
Semaglutide (a GLP-1 receptor agonist) and tirzepatide (a dual GIP/GLP-1 agonist) are compounded together into a single oral dose.
Taken once daily by mouth
The combination is swallowed rather than injected, so it fits a daily routine and avoids weekly needles.
No approved equivalent
No FDA-approved medication combines the two, and no trial has studied them together — so this is a compounded-only format.
Provider-determined
A licensed provider decides whether the combination, a single agent, or no treatment is appropriate for your history.
How it works with Surfbound
Complete your intake
Answer a short health questionnaire from home — history, current medications, and goals. It takes about 5–10 minutes.
A provider reviews your case
An independent licensed provider evaluates whether the compounded combination is medically appropriate, or whether a single agent fits better.
Medication ships if prescribed
If prescribed, your compounded combination ships discreetly from a licensed compounding pharmacy with clear daily dosing instructions.
Surfbound offerings
The combination, and the single-agent alternatives
Surfbound offers the compounded oral combination alongside single-agent oral options, so a provider can match the approach to your situation. Every price is flat and all-inclusive.
Oral combination
Semaglutide + Tirzepatide
1-month supply · prepaid tiers available
- Licensed provider review
- Medication included if prescribed
- Discreet shipping if approved
- No membership fee
- No dose-based price increase
- No charge if not approved
Single-agent oral alternatives
Oral semaglutide
Single-agent daily tablet from a compounded source.
Oral tirzepatide
Dual GIP/GLP-1 daily tablet from a compounded source.
Which option applies is a medical decision. Because no trial has studied the two actives taken together, some providers may recommend a single agent instead of the combination. Surfbound lets your provider determine the appropriate path after reviewing your history.
Flat, all-inclusive pricing
One price covers provider review and medication if prescribed — nothing itemized on top.
No dose-based upcharge
The monthly price does not rise as the prescribed amount changes.
No charge if not approved
Nothing is charged unless your medication is approved.
Pricing shown is an estimate. Final pricing and treatment are determined after licensed provider review. Compounded medications are not FDA-approved and are prescribed only when medically appropriate. Not all patients qualify.
What is known and not known
Being straight about the evidence
The individual medications are well studied. The combination is not. We separate the two clearly so you can make an informed decision with your provider.
What we can say
- Semaglutide and tirzepatide each have their own established evidence base as individual medications.
- Both act on appetite regulation and blood-sugar pathways, and both can cause similar gastrointestinal side effects.
- Combining them could plausibly increase the intensity of those overlapping effects because both act on the same systems.
What remains unknown
- No clinical trial has studied semaglutide and tirzepatide taken together in humans.
- There is no established dosing schedule, long-term safety data, or efficacy data for the combination.
- No regulatory body has approved a fixed-dose product containing both actives.
- Individual responses and the strength provided by a compounding pharmacy may vary.
This page is general information, not medical advice. A licensed provider reviews your individual history to determine whether any treatment is appropriate. Compounded medications are not FDA-approved.
Frequently asked questions
It is a compounded medication that pairs two GLP-1–related active ingredients — semaglutide and tirzepatide — into a single daily oral dose. No FDA-approved product combines semaglutide and tirzepatide, and no clinical trial has studied taking the two together, so a compounded combination is the only format in which both appear in one dose.
At Surfbound Health the compounded oral semaglutide + tirzepatide combination starts at $365 per month, all-inclusive. The price covers licensed provider review and the medication when prescribed, with no membership fee and no insurance required. Multi-month prepaid supplies lower the effective monthly cost.
The combination is taken by mouth, typically as a single daily dose, instead of as a weekly injection. Your licensed provider sets the starting amount and any adjustments based on your health history and how you respond. Exact instructions come with your medication if it is prescribed.
No clinical trial has studied the two taken together, so the combined safety and efficacy profile is not established. Both act on overlapping appetite and blood-sugar pathways, which may compound effects and side effects. A licensed provider reviews your history to decide whether the combination, a single agent, or no treatment is appropriate. Common side effects of GLP-1 medications include nausea, vomiting, diarrhea, and constipation.
A single-agent option uses either semaglutide or tirzepatide on its own. The combination places both in one compounded dose. Surfbound offers single-agent oral semaglutide ($199/mo), single-agent oral tirzepatide ($319/mo), and the combination from $365/mo, so a provider can match the option to your situation.
Yes, a prescription is required. You complete a secure online intake, an independent licensed provider reviews it, and if the combination is medically appropriate the compounded medication ships discreetly from a licensed compounding pharmacy. No appointment or in-person visit is required.
No. Compounded semaglutide + tirzepatide combination medications are not FDA-approved finished drug products. The FDA has not evaluated them for safety, efficacy, or quality. They are prepared by licensed compounding pharmacies for individual patients and prescribed only when a provider determines they are medically appropriate.
Nothing is charged unless your medication is approved. Once treatment is approved and pharmacy processing begins, payment becomes nonrefundable, consistent with the Surfbound refund policy.
Two actives, one daily dose
The compounded oral semaglutide + tirzepatide combination starts at $365/mo, all-inclusive. Complete your intake online in minutes — a licensed provider reviews it and, if the combination is appropriate, medication ships to your door. Nothing is charged unless your medication is approved.
Start onlinePrescription required. Not everyone qualifies. No FDA-approved combination exists. Compounded medications are not FDA-approved and are prescribed only when medically appropriate.